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  • Do PIs really understand the submission process?

    Youre all on the same team right? At times it doesnt seem so. Sometimes, the way people look at the IRB process and its documentation is that its just one more hurdle they have to jump through in order to conduct their research, says Sarah Frankel, PhD, education specialist at the Human Studies Committee of Washington University School of Medicine in St. Louis.
  • Public education program successful with PAD trial

    The Public Access Defibrillation (PAD) trial experience offers clinical trial administrators a firsthand look at how to conduct extensive public education in the absence of individual informed consent.
  • Hopkins studies effect of violence on children

    In a popular music video, the star is shot in one scene, then in the next, a small plastic bandage covers the purported wound as he continues singing with an arrogant swagger into the next verse. Guns and images of violence are popular entertainment in this country featured in the plot lines of popular movies, music videos, TV shows, and video games.
  • News Brief

    The Office for Human Research Protections (OHRP) has released an updated set of Human Subject Regulations Decision Charts, which can help IRBs determine whether an activity amounts to human subjects research that falls within the realm of the IRBs review process.
  • Full December 2004 issue in PDF

  • Malaria Risk in Travelers

    The GeoSentinel surveillance database was examined to identify patient and travel characteristics associated with the acquisition of malaria. Travel to sub-Saharan Africa and Oceania had the highest relative risk for acquisition of malaria infections. The most common reason for travel among malaria patients was to visit friends and relatives (VFR).
  • Reducing Deaths From Malaria

    Death occurred in about 1 per 100 cases of malaria diagnosed in U.S. travelers from 1963 to 2001, and many factors contribute to death from malaria. Most were preventable, and people returning home to visit friends and relatives have now become the leading risk group for malaria-related deaths.
  • Acute Mountain Sickness Prevention: How Much Acetazolamide is Needed?

    A recent study suggests that 250 mg doses of acetazolamide might be more effective than 125 mg doses in combating acute mountain sickness. Nonetheless, the applicability of these findings to travelers reaching high altitudes remains unclear.
  • Full December 2004 issue in PDF

  • The Changing Face of Bacterial Meningitis

    The mortality associated with bacterial meningitis remains high, and the strongest risk factors for an unfavorable outcome are those that are indicative of systemic compromise, a low level of consciousness, and infection with S. pneumoniae.